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Drug database

This database contains suggested safety information about the interaction of specific drugs in patients with porphyria.

You can search this database by the drug class, drug type, generic name, brand name, or by suggested safety status. If you are unclear of a drug's correct spelling, try entering the first letter(s) of the drug's brand name or generic name. For example, if you are searching for Motrin, try entering an M into the brand name field.

Drug class:
Drug type:
Generic name:
Brand name:
Status:
 

Definitions

OK! = very likely to be safe for prolonged use by individuals with an acute porphyria, based on consistent evidence

OK? = probably safe for prolonged use by individuals with an acute porphyria, based on evidence that is either inconsistent or insufficient to be conclusive

BAD? = probably unsafe for prolonged use by individuals with an acute porphyria, based on evidence that is either inconsistent or insufficient to be conclusive

BAD! = very likely to be unsafe for prolonged use by individuals with an acute porphyria, based on consistent evidence

NO INFO = information insufficient for deriving any conclusion

 

Acknowledgments

The following individuals, who contributed their knowledge and expertise to the development of this drug list, receive our sincere thanks:

  • The authors of this list: Bo Zhou and Peter V. Tishler, M. D., Channing Laboratory and Genetics Division, Brigham & Women's Hospital, Boston, MA

  • Numerous patients with an acute porphyria

  • Drs. Karl E. Anderson, D. Montgomery Bissell, Joseph R. Bloomer, Herbert L. Bonkovsky

  • Physicians at Harvard Medical School and/or the Brigham & Women’s Hospital:  Ronald A. Arky, Edward B. Bromfield, Dawn L. Demeo, Sunil Eappen, Christopher H. Fanta, Samuel Z. Goldhaber, Norton J. Greenberger, Koenraad J. Mortele, Louis R. Pasquale (Massachusetts Eye & Ear Infirmary), Edgar L. Ross, Judith M. Strymish (VA Boston Healthcare System), Lewis R. Sudarsky,  Chinweike Ukumadu, Bernardino Vaccaro, Stephen D. Wiviott

  • Drs. Barbara W. LeDuc and David A. Williams of the Massachusetts College of Pharmacy and Health Sciences

  • All individuals who contributed to existent drug lists: the Scandinavian drug database (especially Drs. Atle Brun  and Stig Thunell), the University of Cape Town Porphyria Service drug database, the European Porphyria Initiative, and the Porphyria Research Unit of Professor Michael Moore of the University of Queensland

  • The members of the American Porphyria Foundation for their financial and administrative support

  • Ms. Nina Zonnevylle of the Brigham & Women’s Hospital (for administrative support)

 

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